LSBio
SQSTM1 Antibody

Anti-SQSTM1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

SQSTM1 Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
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$556.00each
Catalog Number: LS-B4617-0.05

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Overview

Description
SQSTM1 antibody LS-B4617 is an unconjugated rabbit polyclonal antibody to SQSTM1 from human. It is reactive with human, mouse and rat. Validated for ELISA, IF, IHC and WB. Cited in 2 publications.
Application
ELISA, IF, IHC, IHC-P, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
A170 | ORCA | OSIL | Paget disease of bone 3 | p60 | p62 | PDB3 | Sequestosome-1 | Ubiquitin-binding protein p62 | Oxidative stress induced like | p62B | ZIP3 | Sequestosome 1 | SQSTM1 | EBI3-associated protein p60 | EBIAP
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
1 - 2 µg/ml
UniProt Number
Q13501
SwissProt
Q13501

Target

Target
SQSTM1
Antigen Species
Human
Gene Name
SQSTM1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A 14 AA synthetic peptide near the C-Terminus of human SQSTM1. The immunogen is located within the last 50 AA of SQSTM1.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS containing 0.02% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C for up to 1 year.
Recommended Storage Buffer
PBS

Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity. Hubbs AF, Fluharty KL, Edwards RJ, Barnabei JL, Grantham JT, Palmer SM, Kelly F, Sargent LM, Reynolds SH, Mercer RR, Goravanahally MP, Kashon ML, Honaker JC, Jackson MC, Cumpston AM, Goldsmith WT, McKinney W, Fedan JS, Battelli LA, Munro T, Bucklew-Moyers W, McKinstry K, Schwegler-Berry D, Friend S, Knepp AK, Smith SL, Sriram K. The American journal of pathology. 2016;186:2887-2908.

PubMed: 27643531 · PMC: PMC5222965


Improved efficacy of a next-generation ERT in murine Pompe disease. Xu S, Lun Y, Frascella M, Garcia A, Soska R, Nair A, Ponery AS, Schilling A, Feng J, Tuske S, Valle MCD, Martina JA, Ralston E, Gotschall R, Valenzano KJ, Puertollano R, Do HV, Raben N, Khanna R. JCI insight. 2019 March;4:pii: 125358.

PubMed: 30843882 · PMC: PMC6483515

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