LSBio
SLC22A2 Antibody (aa524-555)

SLC22A2 antibody Western blot. All lanes: Anti SLC22A2 at 0.5 ug/ml. Lane 1: Rat Brain Tissue Lysate at 50 ug. Lane 2: Mouse Brain Tissue Lysate at 50 ug. Predicted band size: 63 kD. Observed band size: 63 kD.

SLC22A2 Antibody (aa524-555)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse, Rat
Format:Lyophilized
See all Human SLC22A2 antibodies →
$480.00each
Catalog Number: LS-C357581-100

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Overview

Description
SLC22A2 antibody LS-C357581 is an unconjugated rabbit polyclonal antibody to SLC22A2 (aa524-555) from human. It is reactive with human, mouse and rat. Validated for IHC and WB. Cited in 1 publication.
Application
IHC, IHC-P, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
HOCT2 | OCT2 | Organic cation transporter 2 | SLC22A2
UniProt Number
O15244
SwissProt
O15244

Target

Target
Human SLC22A2
Antigen Species
Human
Epitope
Mainly expressed in kidney. Localized at the luminal membrane and basolateral membrane of kidney distal tubule and proximal tubules. To a lower extent, expressed in neurons of the cerebral cortex and in various subcortical nuclei (at protein levels). Also detected in secretory phase endometrium; in scattered cells in the stroma. .
Gene Name
SLC22A2

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human SLC22A2 (524-555 aa ETIEEAENMQRPRKNKEKMIYLQVQKLDIPLN), different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg sodium azide.
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
Recommended Storage Buffer
NaCl
The Role of NF-kB in the Downregulation of Organic Cation Transporter 2 Expression and Renal Cation Secretion in Kidney Disease. Chao Han, Juan Zheng, Fengyi Wang, Qingyang Lu, Qingfa Chen, Ankang Hu, Michele Visentin, Gerd A Kullak-Ublick, Zhibo Gai, Lei Chu. Frontiers in medicine. 2022 January;8:800421. PubMed: 35059420 PMC: PMC8763702

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