LSBio
SLC1A2 / EAAT2 / GLT-1 Antibody (aa546-565)

SLC1A2 / EAAT2 / GLT-1 Antibody (aa546-565)

Primary AntibodyLSBio Guarantee
Antibody:Guinea Pig Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Human, Mouse, Non-Human Primate, Rabbit, Rat
Format:Liquid
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$900.00each
Catalog Number: LS-C15448-50

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Overview

Description
GLT-1 antibody LS-C15448 is an unconjugated guinea pig polyclonal antibody to GLT-1 (SLC1A2 / EAAT2) (aa546-565) from rat. It is reactive with human, mouse, rat and other species. Validated for IHC. Cited in 1 publication.
Application
IHC
Reactivity
Hu, Ms, NHP, Rb, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
EAAT-2 | GLT-1 | Glutamate transporter 1 | SLC1A2 | EAAT2 | GLT1
Recommended Dilution: IHC
1:1000 - 1:4000
UniProt Number
P43004
SwissProt
P43004

Target

Target
Rat SLC1A2 / EAAT2 / GLT-1
Antigen Species
Rat
Epitope
Recognizes rat Glial Glutamate Transporter GLT-1 (EAAT2). Species Reactivity: Rat. Species sequence homology: human.
Gene Name
SLC1A2

Antibody

Host Species
Guinea Pig
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Synthetic peptide (AANGKSADCSVEEEPWKREK) from the C-Terminus of rat GLT-1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Rabbit (100%); Bat, Bovine, Dog, Pig (95%); Horse (90%); Turkey, Chicken, Platypus (80%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
0.05% Sodium Azide
Volume
50 Microliter
Preservative
Yes
Purification Method
Unpurified (Serum / Ascites / Supernatant)

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Pharmacological inhibitions of glutamate transporters EAAT1 and EAAT2 compromise glutamate transport in photoreceptor to ON-bipolar cell synapses. Tse DY, Chung I, Wu SM. Vision research. 2014;103:49-62. PubMed: 25152321 PMC: PMC4547049

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