Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Recombinant Monoclonal Rabbit anti-Rabbit ITGB7 / Integrin Beta 7 Antibody (clone FIB27)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Blocking / Competition Assay, Flow Cytometry, Immunoprecipitation |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$551.00each
Catalog Number: LS-C821486-0.2
Catalog Number: LS-C821486
For bulk orders or custom formulations:
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- Description
- This ITGB7 / Integrin Beta 7 antibody is an unconjugated Rabbit/Rat chimeric recombinant monoclonal antibody. Validated for Block, Flo, and IP.
- Application
- Blocking, FC, IP
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- Integrin Beta 7 | Integrin beta 7 subunit | Integrin beta-7 | Integrin, beta 7 | ITGB7 | INTEGRINB7 | Integrin B7 | Integrin B 7
- UniProt Number
- P26010
- NCBI GenBank
- NM_000889 | NP_000880.1
- SwissProt
- P26010
Target
- Target
- Rabbit ITGB7 / Integrin Beta 7
- Antigen Species
- Rabbit
- Epitope
- FIB27 binds specifically to both human and mouse integrin beta-7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta-7 is one subunit is a heterodimer which makes up an intergin molecule. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
- Gene Name
- ITGB7
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- FIB27
- Isotype
- IgG
- Light Chain
- Kappa Light Chain
- Origin Species
- Human
Immunogen
- Immunogen
- FIB27 was prepared by immunizing rats with TK1 cells.
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.02% Proclin 300
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store undiluted at 4°C for up to 3 months. Aliquot and store at -20°C for long term storage.
- Recommended Storage Buffer
- PBS