Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Formalin-fixed, paraffin-embedded human Ewing's Sarcoma stained with NKX2.2 Mouse Recombinant Monoclonal Antibody (rNX2/1523).
Recombinant Monoclonal Mouse anti-Human NKX2-2 Antibody (clone rNX2/1523, aa1-119, IHC)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751301-20
Catalog Number: LS-C751301
For bulk orders or custom formulations:
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- Description
- NKX2-2 antibody LS-C751301 is an unconjugated mouse recombinant monoclonal antibody to human NKX2-2 (aa1-119). Validated for IHC.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- Homeobox protein Nkx-2.2 | NK-2 (Drosophila) homolog B | NK2 homeobox 2 | NKX2.2 | NKX2-2 | NKX2B | NK-2 homolog B
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P42586
- NCBI GenBank
- NP_035049.1
- SwissProt
- P42586
Target
- Target
- Human NKX2-2
- Antigen Species
- Human
- Epitope
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
- Gene Name
- Nkx2-2
Antibody
- Host Species
- Mouse
- Clonality
- Recombinant Monoclonal
- Clone
- rNX2/1523
- Isotype
- IgG1
- Origin Species
- Mouse
Immunogen
- Immunogen
- Human recombinant NKX2.2 protein fragment (around aa1-119). Antigen Molecular Weight: 40-50 kDa
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS