Human Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ NKX2-2 Antibody (clone rNX2/294)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Recombinant Monoclonal
Applications:	Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

$536.00each

Catalog Number: LS-B16255-100

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Description: NKX2-2 antibody LS-B16255 is an unconjugated mouse recombinant monoclonal antibody to human NKX2-2. Validated for IHC.
Application: IHC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: Homeobox protein Nkx-2.2 | NK-2 (Drosophila) homolog B | NK2 homeobox 2 | NKX2.2 | NKX2-2 | NKX2B | NK-2 homolog B
Recommended Dilution: IHC-P: 1:50
UniProt Number: P42586
NCBI GenBank: NP_035049.1
SwissProt: P42586

Target: NKX2-2
Antigen Species: Human
Specificity: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Epitope: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Gene Name: Nkx2-2