LSBio
Polyclonal Rabbit anti-Human SCRN1 / Secernin 1 Antibody (aa10-37, IHC, WB)

Western blot of lysate from U-251 MG cell line, using SCRN1 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Polyclonal Rabbit anti-Human SCRN1 / Secernin 1 Antibody (aa10-37, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
See all Human SCRN1 / Secernin 1 antibodies →
$401.00each
Catalog Number: LS-C162903-400

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Overview

Description
Secernin 1 antibody LS-C162903 is an unconjugated rabbit polyclonal antibody to Secernin 1 (SCRN1) (aa10-37) from human. It is reactive with human and mouse. Validated for Flow, IHC and WB. Cited in 3 publications.
Application
FC, IHC, IHC-P, WB
Reactivity
Hu
Predicted Reactivity
Bovine, Mouse, Rat
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
KIAA0193 | Secernin-1 | SES1 | SCRN1 | Secernin 1
Recommended Dilution: FC
1:10 - 1:50
Recommended Dilution: IHC-P
1:50 - 1:100
Recommended Dilution: WB
1:1000
UniProt Number
Q12765
SwissProt
Q12765

Target

Target
Human SCRN1 / Secernin 1
Antigen Species
Human
Epitope
This SCRN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human SCRN1.
Gene Name
SCRN1

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
0.5 mg/mL
Volume
400 Microliter
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Recommended Storage Buffer
PBS

Proteomic differences in amyloid plaques in rapidly progressive and sporadic Alzheimer's disease. Drummond E, Nayak S, Faustin A, Pires G, Hickman RA, Askenazi M, Cohen M, Haldiman T, Kim C, Han X, Shao Y, Safar JG, Ueberheide B, Wisniewski T. Acta neuropathologica. 2017 June;133:933-954.

PubMed: 28258398 · PMC: PMC5503748


Phosphorylated tau interactome in the human Alzheimer's disease brain. Eleanor Drummond, Geoffrey Pires, Claire MacMurray, Manor Askenazi, Shruti Nayak, Marie Bourdon, Jiri Safar, Beatrix Ueberheide, Thomas Wisniewski. Brain : a journal of neurology. 2020 September;143:2803-2817.

PubMed: 32812023 · PMC: PMC7526722


Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer's disease and not in other tauopathies. Geoffrey Pires, Sacha McElligott, Shiron Drusinsky, Glenda Halliday, Marie-Claude Potier, Thomas Wisniewski, Eleanor Drummond. Acta neuropathologica communications. 2019 Dec;7:195.

PubMed: 31796108 · PMC: PMC6892024

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