Polyclonal Rabbit anti-Human SLC5A11 / SMIT2 Antibody (WB)
Catalog Number: LS-C748223
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Western blot analysis of lysates from COS7 cells, using MITF (Phospho-Ser180/73) Antibody. The lane on the right is blocked with the phospho peptide.
Polyclonal Rabbit anti-Human MITF Antibody (phospho-Ser180/Ser73, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$341.00each
Catalog Number: LS-C199259-50
Catalog Number: LS-C199259
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- MITF antibody LS-C199259 is an unconjugated rabbit polyclonal antibody to MITF (pSer180/Ser73) from human. It is reactive with human and mouse. Validated for Peptide-ELISA and WB. Cited in 2 publications.
- Application
- ELISA, IHC, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- BHLHe32 | CMM8 | MI | MITF | Waardenburg syndrome, type 2A | WS2 | WS2A
- Recommended Dilution: WB
- 1:500 - 1:1000
- UniProt Number
- O75030
- NCBI GenBank
- NM_000248 | NP_000239.1
- SwissProt
- O75030
Target
- Target
- Human MITF
- Antigen Species
- Human
- Epitope
- MITF (Phospho-Ser180/73) Antibody detects endogenous levels of MITF only when phosphorylated at serine180/73.
- Gene Name
- MITF
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Synthetic peptide derived from human MITF around the phosphorylation site of Ser180/73. (AA Range: 151-200)
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
- Concentration
- 1 mg/mL
- Volume
- 50 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS|150 mM NaCl
Mitochondrial dynamics regulate melanogenesis through proteasomal degradation of MITF via ROS-ERK activation. Kim ES, Park SJ, Goh MJ, Na YJ, Jo DS, Jo YK, Shin JH, Choi ES, Lee HK, Kim JY, Jeon HB, Kim JC, Cho DH. Pigment cell & melanoma research. Nov;27:1051-62.
PubMed: 25065405
Conditioned Media from Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Inhibits Melanogenesis by Promoting Proteasomal Degradation of MITF. Kim ES, Jeon HB, Lim H, Shin JH, Park SJ, Jo YK, Oh W, Yang YS, Cho DH, Kim JY. PloS one. 2015;10:e0128078.
PubMed: 26024475 · PMC: PMC4449211
