LSBio
Polyclonal Rabbit anti-Human IBSP / Bone Sialoprotein Antibody (N-Terminus, WB)

Polyclonal Rabbit anti-Human IBSP / Bone Sialoprotein Antibody (N-Terminus, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunoprecipitation, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
See all Human IBSP / Bone Sialoprotein antibodies →
$702.00each
Catalog Number: LS-C190916-100

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Overview

Description
Bone Sialoprotein antibody LS-C190916 is an unconjugated rabbit polyclonal antibody to Bone Sialoprotein (IBSP) (N-Terminus) from human. It is reactive with human, mouse and rat. Validated for IP and WB. Cited in 2 publications.
Application
IHC, IP, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Bone Sialoprotein | Bone sialoprotein II | BSP | BSP II | Cell-binding sialoprotein | BNSP | Bone Sialprotein II | IBSP | Integrin-binding sialoprotein | Bone sialoprotein 2 | BSP-II | SP-II
Recommended Dilution: IP
1:50
Recommended Dilution: WB
1:1000
UniProt Number
P21815
SwissProt
P21815

Target

Target
Human IBSP / Bone Sialoprotein
Antigen Species
Human
Epitope
Endogenous levels of total human IBSP. Species Crossreactivity: Mouse and rat.
Gene Name
IBSP

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic peptide corresponding to residues near the N-Terminus of human IBSP.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM HEPES-Sodium, pH 7.5, 150 mM NaCl, 100ug/ml BSA, 50% Glycerol
Volume
100 Microliter
Preservative
No
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for up to 1 year.
Recommended Storage Buffer
10 mM HEPES|150 mM NaCl

Human immunodeficiency virus type 1 enhancer-binding protein 3 is essential for the expression of asparagine-linked glycosylation 2 in the regulation of osteoblast and chondrocyte differentiation. Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, Nagano S, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S. The Journal of biological chemistry. 2014 Apr;289:9865-79.

PubMed: 24563464 · PMC: PMC3975031


BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts. Yuhei Yahiro #, Shingo Maeda #, Masato Morikawa, Daizo Koinuma, Go Jokoji, Toshiro Ijuin, Setsuro Komiya, Ryoichiro Kageyama, Kohei Miyazono, Noboru Taniguchi. Bone research. 2020 September;8:32.

PubMed: 32923015 · PMC: PMC7463266

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