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Polyclonal Rabbit anti-Human HIF3A / HIF3-Alpha Antibody (aa497-514, WB)

WB of HIF3A / HIF3-Alpha antibody. WB: Rat Brain Tissue Lysate.

Polyclonal Rabbit anti-Human HIF3A / HIF3-Alpha Antibody (aa497-514, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Western Blot
Reactivity:Human, Non-Human Primate, Rat
Format:Lyophilized
See all Human HIF3A / HIF3-Alpha antibodies →
$480.00each
Catalog Number: LS-C313254-100

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Overview

Description
HIF3-Alpha antibody LS-C313254 is an unconjugated rabbit polyclonal antibody to HIF3-Alpha (HIF3A) (aa497-514) from human. It is reactive with human, rat and monkey. Validated for WB.
Application
WB
Reactivity
Hu, NHP, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
BHLHe17 | HIF-3A | IPAS | HIF3-alpha-1 | HIF3A | Inhibitory PAS domain protein | PASD7 | HIF-3-alpha | HIF3-alpha | Member of PAS protein 7 | MOP7
UniProt Number
Q9Y2N7
NCBI GenBank
NM_152795 | NP_690008.2
SwissProt
Q9Y2N7

Target

Target
Human HIF3A / HIF3-Alpha
Antigen Species
Human
Epitope
Expressed in vascular cells (at protein level) (PubMed:21069422). Expressed in kidney (PubMed:11573933, PubMed:19694616). Expressed in lung epithelial cells (PubMed:16775626). Expressed in endothelial cells (venous and arterial cells from umbilical cord and aortic endothelial cells) and in vascular smooth muscle cells (aorta) (PubMed:21069422). Strongly expressed in the heart, placenta, and skeletal muscle, whereas a weak expression profile was found in the lung, liver, and kidney (PubMed:12538644). Expressed weakly in cell renal cell carcinoma (CC-RCC) compared to normal renal cells (PubMed:16126907). Expression is down-regulated in numerous kidney tumor cells compared to non tumor kidney tissues (PubMed:16126907). Isoform 2 is expressed in heart, placenta, lung, liver, skeletal muscle and pancreas and in numerous cancer cell lines (PubMed:20416395). Isoform 3 and isoform 4 are weakly expressed in heart, placenta, lung, liver, skeletal muscle and pancreas (PubMed:20416395). Isoform 4 is expressed in fetal tissues, such as heart, brain, thymus, lung, liver, skeletal kidney and spleen (PubMed:20416395). Isoform 3 is weakly expressed in fetal tissues, such as liver and kidney (PubMed:20416395). .
Gene Name
HIF3A

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
A synthetic peptide corresponding to a sequence at the C-Terminus of human HIF3(497-514 aa DDDFQLNASEQLPRAYHR), different from the related rat and mouse sequences by five amino acids.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg Thimerosal, 0.05mg sodium azide.
Concentration
0.5 mg/mL
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
Recommended Storage Buffer
NaCl

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