LSBio
Polyclonal Rabbit anti-Human DOCK7 Antibody (IF, WB)

Positive WB detected in:Jurkat whole cell lysate,Hela whole cell lysate;All lanes: DOCK7 antibody at 3ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 243,242,239,73,240 kDa;Observed band size: 243 kDa;

Polyclonal Rabbit anti-Human DOCK7 Antibody (IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Western Blot
Reactivity:Human
Format:Liquid
See all Human DOCK7 antibodies →
$300.00each
Catalog Number: LS-C501214-50

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Overview

Description
DOCK7 antibody LS-C501214 is an unconjugated rabbit polyclonal antibody to human DOCK7. Validated for ELISA, IF and WB.
Application
ELISA, IF, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Dedicator of cytokinesis 7 | KIAA1771 | ZIR2 | DOCK7
UniProt Number
Q96N67
NCBI GenBank
AB051558
SwissProt
Q96N67

Target

Target
Human DOCK7
Antigen Species
Human
Epitope
Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Gene Name
DOCK7

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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