LSBio
Polyclonal Rabbit anti-Human DOCK7 Antibody (HRP)

Polyclonal Rabbit anti-Human DOCK7 Antibody (HRP)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay
Reactivity:Human
Format:Liquid
See all Human DOCK7 antibodies →
$300.00each
Catalog Number: LS-C501223-50

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Overview

Description
DOCK7 antibody LS-C501223 is an HRP-conjugated rabbit polyclonal antibody to human DOCK7. Validated for ELISA.
Application
ELISA
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Dedicator of cytokinesis 7 | KIAA1771 | ZIR2 | DOCK7
UniProt Number
Q96N67
NCBI GenBank
AB051558
SwissProt
Q96N67

Target

Target
Human DOCK7
Antigen Species
Human
Epitope
Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Gene Name
DOCK7

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Horseradish Peroxidase
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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