LSBio
Polyclonal Rabbit anti-Human CDYL Antibody (IHC)

Immunohistochemistry of paraffin-embedded human glioma cancer using CDYL Antibody at dilution of 1:100

Polyclonal Rabbit anti-Human CDYL Antibody (IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all Human CDYL antibodies →
$300.00each
Catalog Number: LS-C502177-50

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Overview

Description
CDYL antibody LS-C502177 is an unconjugated rabbit polyclonal antibody to human CDYL. Validated for ELISA and IHC.
Application
ELISA, IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CDY-like | CDYL | Chromodomain Y-like protein | CDY-like, autosomal | CDYL1 | Chromodomain protein, Y-like | DKFZP586C1622
UniProt Number
Q9Y232
SwissProt
Q9Y232

Target

Target
Human CDYL
Antigen Species
Human
Epitope
Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.
Gene Name
CDYL

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Chromodomain Y-like protein protein (8-260AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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