Polyclonal Goat anti-Goat Biotin Antibody (FITC, IF)
Catalog Number: LS-C758060-1
1 mg / $322.00
Antibody: Goat Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunofluorescence
Reactivity: Goat
Format: Liquid
Immunohistochemistry of paraffin-embeddedi mouse spleen stained with Goat anti-mouse CD197
Polyclonal Goat anti-Mouse CCR7 Antibody (aa2-22, IHC, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Goat Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Mouse |
| Format: | Liquid |
$436.00each
Catalog Number: LS-C187706-50
Catalog Number: LS-C187706
For bulk orders or custom formulations:
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- Description
- CCR7 antibody LS-C187706 is an unconjugated goat polyclonal antibody to mouse CCR7 (aa2-22). Validated for ELISA, Flow, IHC and WB.
- Application
- ELISA, FC, IHC-P, WB
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- BLR2 | Chemokine (C-C) receptor 7 | CD197 | C-C CKR-7 | CMKBR7 | CC chemokine receptor 7 | CCR-7 | CCR7 | CD197 antigen | CDw197 | EBI1 | EVI1 | MIP-3 beta receptor | C-c chemokine receptor 7 | C-C chemokine receptor type 7 | CC-CKR-7 | Chemokine c-c motif receptor 7
- Recommended Dilution: ELISA
- 1:100000
- Recommended Dilution: FC
- 1:10
- Recommended Dilution: IHC-P
- 1:250
- Recommended Dilution: WB
- 1:1000
- UniProt Number
- P32248
- NCBI GenBank
- NM_001838 | NP_001829.1
- SwissProt
- P32248
Target
- Target
- Mouse CCR7
- Antigen Species
- Mouse
- Epitope
- Recognizes mouse C-C chemokine receptor type 7, also known as CD197, CCR7, Epstein-Barr virus-induced G-protein coupled receptor 1 or MIP-3 beta receptor. CD197 is a 378 amino acid ~43 kD multi pass type III transmembrane glycoprotein and member of the G-protein coupled receptor 1 family. CD197 is expressed by various lymphoid tissues, activated B and T cells, naive T cells, NK cells and dendritic cells (DCs), which acts a high-affinity receptor for the chemokines MIP-3beta (CCL19) and CCL21. Ligand binding of CD197 plays a vital role in the homing of naive T cells and antigen-loaded DCs into secondary organs. Expression of CD197 is strongly up-regulated in B cells infected with Epstein-Barr virus (EBV) and T cells infected with herpesvirus 6 or 7. Can be used in research studies to distinguish between central memory and effector memory T cells and is reported as suitable for use in immunocytochemistry.
- Gene Name
- CCR7
Antibody
- Host Species
- Goat
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acids 2-22 of mouse CD197. Percent identity by BLAST analysis: Mouse (100%); Rat, Hamster, Bovine (90%); Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (86%); Orangutan, Galago, Ferret, Dog, Cat, Horse (81%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.1% Sodium Azide, 0.1% BSA
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS
