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PathPlus™ Recombinant Monoclonal Rabbit anti-Human CD34 Antibody (clone HPCA1/2598R, IHC)

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ Recombinant Monoclonal Rabbit anti-Human CD34 Antibody (clone HPCA1/2598R, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
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$536.00each
Catalog Number: LS-B16265-100

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Overview

Description
CD34 antibody LS-B16265 is an unconjugated rabbit recombinant monoclonal antibody to human CD34. Validated for Flow and IHC.
Application
FC, IHC, IHC-P
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
CD34 | CD34 molecule | CD34 antigen | HPCA1
Recommended Dilution: FC
0.5 - 1 µg/10E6 cells
Recommended Dilution: IHC-P
1:100
UniProt Number
P28906
SwissProt
P28906

Target

Target
CD34
Antigen Species
Human
Specificity
This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120 kDa , which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but shows low specificity.
Epitope
This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120 kDa , which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but shows low specificity.
Gene Name
CD34

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
HPCA1/2598R
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length human HPCA1 protein. Antigen Molecular Weight: 90-110 kDa
Immunogen Type
Full-Length Recombinant Protein

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.