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PathPlus™ Polyclonal Rabbit anti-Human BDKRB2/Bradykinin B2 Receptor Antibody (C-Terminus, IHC)

Anti-BDKRB2/Bradykinin B2 Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PathPlus™ Polyclonal Rabbit anti-Human BDKRB2/Bradykinin B2 Receptor Antibody (C-Terminus, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Human, Mouse, Rat
Format:Liquid
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$403.00each
Catalog Number: LS-A797-50

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Overview

Description
Bradykinin B2 Receptor antibody LS-A797 is an unconjugated rabbit polyclonal antibody to Bradykinin B2 Receptor (BDKRB2) (C-Terminus) from human. It is reactive with human, mouse and rat. Validated for ICC and IHC. Cited in 4 publications.
Application
IHC
Reactivity
Hu, Ms, Rt
Predicted Reactivity
Non-Human Primate
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
BDKRB2 | BK-2 receptor | Bradykinin type-2 receptor | B2R | Bradykinin B2 receptor | BRB2 | BK-2R | BK-2Rs | BK2 | B2 bradykinin receptor | B2bkr | BK-2 | BKR2 | Bradykinin receptor B2
Recommended Dilution: IHC-P
5 - 10 µg/ml
UniProt Number
P30411
SwissProt
P30411

Target

Target
BDKRB2/Bradykinin B2 Receptor
Antigen Species
Human
Specificity
Human BDKRB2 / BK-2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BAHD1 (44%).
Epitope
Human BDKRB2 / BK-2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BAHD1 (44%).
Gene Name
BDKRB2

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 18 amino acid peptide from C-Terminus of human BDKRB2 / BK-2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (94%); Mouse, Pig (83%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation. Savard M, Barbaz D, Blanger S, Mller-Esterl W, Bkaily G, D'orlans-Juste P, Cot J, Bovenzi V, Gobeil F. Journal of cellular physiology. 2008;216:234-44.

PubMed: 18264983


Immunohistochemical localization of the bradykinin B1 and B2 receptors in human nasal mucosa. Shirasaki H, Kanaizumi E, Himi T. Mediators of inflammation. 2009;2009:102406.

PubMed: 19404481 · PMC: PMC2673475


Structure-activity relationships of novel peptide agonists of the human bradykinin B2 receptor. B[Character e9]langer S, Bovenzi V, C[Character f4]t[Character e9] J, Neugebauer W, Amblard M, Martinez J, Lammek B, Savard M, Gobeil F. Peptides. 2009 Apr;30:777-87.

PubMed: 19111586


Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer. Dubuc C, Savard M, Bovenzi V, Lessard A, Fortier A, Côté J, Neugebauer W, Rizzolio F, Geha S, Giordano A, Chemtob S, Gobeil F. Oncotarget. 2018 January;9:9885-9906.

PubMed: 29515778 · PMC: PMC5839409

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