LSBio
PathPlus™ LTB4R2 / BLT2 Antibody (Cytoplasmic Domain)

Anti-LTB4R2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PathPlus™ LTB4R2 / BLT2 Antibody (Cytoplasmic Domain)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Human, Non-Human Primate
Format:Liquid
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$403.00each
Catalog Number: LS-A2099-50

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Overview

Description
BLT2 antibody LS-A2099 is an unconjugated rabbit polyclonal antibody to BLT2 (LTB4R2) (Cytoplasmic Domain) from human. It is reactive with human and monkey. Validated for Flow and IHC. Cited in 2 publications.
Application
IHC
Reactivity
Hu, NHP
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
blt2 | BLT2 | BLTR2 | Blt-2 | BLT2R | JULF2 | LTB4-R2 | LTB4R2 | Hblt2 | KPG_004 | Leukotriene B4 receptor 2 | Leukotriene B4 receptor BLT2 | LTB4 receptor JULF2 | LTB4-R 2
Recommended Dilution: IHC-P
26 µg/ml
UniProt Number
Q9NPC1
SwissProt
Q9NPC1

Target

Target
LTB4R2 / BLT2
Antigen Species
Human
Specificity
Human LTB4R2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Epitope
Human LTB4R2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
LTB4R2

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human LTB4R2. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Mouse, Rat, Bat (88%); Elephant (81%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. Bck M, Bu DX, Brnstrm R, Sheikine Y, Yan ZQ, Hansson GK. Proceedings of the National Academy of Sciences of the United States of America. 2005;102:17501-6.

PubMed: 16293697 · PMC: PMC1297663


Leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through signal transducer and activator of transcription 3 (STAT3)-dependent up-regulation of matrix metalloproteinase 2. Seo JM, Park S, Kim JH. The Journal of biological chemistry. 2012 Apr;287:13840-9.

PubMed: 22396544 · PMC: PMC3340142

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