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PathPlus™ DNMT / DNMT1 Antibody (aa891-904)

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ DNMT / DNMT1 Antibody (aa891-904)

Primary AntibodyLSBio Guarantee
Antibody:Goat Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Bovine, Dog, Horse, Human, Mouse, Non-Human Primate, Pig, Rabbit, Rat, Sheep
Format:Liquid
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$383.00each
Catalog Number: LS-B4353-50

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Overview

Description
DNMT1 antibody LS-B4353 is an unconjugated goat polyclonal antibody to DNMT1 (DNMT) (aa891-904) from human. It is reactive with human, mouse, rat and other species. Validated for IHC, Peptide-ELISA and WB. Cited in 2 publications.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Bov, Can, Hr, Hu, Ms, NHP, Por, Rb, Rt, Sh
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
AIM | CXXC finger protein 9 | CXXC9 | DNA methyltransferase 1 | DNMT | DNA methyltransferase HsaI | DNA MTase HsaI | HSN1E | M.HsaI | MCMT | DNMT1
Recommended Dilution: IHC-P
3.75 µg/ml
Recommended Dilution: WB
0.5 - 1.5 µg/ml
UniProt Number
P26358
SwissProt
P26358

Target

Target
DNMT / DNMT1
Antigen Species
Human
Specificity
Human DNMT1.
Epitope
Human DNMT1.
Gene Name
DNMT1

Antibody

Host Species
Goat
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Peptide with sequence C-RFESPPKTQPTEDN, from the internal egion of the protein sequence according to NP_001370.1 .
Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
TBS

Structural equation modelling analysis determining causal role among methyltransferases, methylation, and apoptosis during human pregnancy and abortion. Nishat Fatima, Syed Habeeb Ahmed, S S Chauhan, Owais Mohammad, Syed Mohd Fazlur Rehman. Scientific reports. 2020 July;10:12408.

PubMed: 32709893 · PMC: PMC7381664


Black raspberries demethylate Sfrp4, a WNT pathway antagonist, in rat esophageal squamous cell papilloma. Yi-Wen Huang, Fei Gu, Alan Dombkowski, Li-Shu Wang, Gary D Stoner. Molecular carcinogenesis. 2016 November;55:1867-1875.

PubMed: 27696538

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