LSBio
IHC-plus™ Polyclonal Rabbit anti-Human DNMT / DNMT1 Antibody (aa1603-1616, IHC)

Anti-DNMT1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ Polyclonal Rabbit anti-Human DNMT / DNMT1 Antibody (aa1603-1616, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all DNMT / DNMT1 antibodies →
$383.00each
Catalog Number: LS-B800-50

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Overview

Description
DNMT1 antibody LS-B800 is an unconjugated rabbit polyclonal antibody to human DNMT1 (DNMT) (aa1603-1616). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IHC, IHC-P
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
AIM | CXXC finger protein 9 | CXXC9 | DNA methyltransferase 1 | DNMT | DNA methyltransferase HsaI | DNA MTase HsaI | HSN1E | M.HsaI | MCMT | DNMT1
Recommended Dilution: ELISA
1:1000
Recommended Dilution: IHC-P
10 µg/ml
UniProt Number
P26358
SwissProt
P26358

Target

Target
DNMT / DNMT1
Antigen Species
Human
Specificity
Amino acids 1603 to 1616 of human DNMT1
Epitope
Amino acids 1603 to 1616 of human DNMT1
Gene Name
DNMT1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide from human DNMT1.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis. Kristensen DG, Nielsen JE, Jørgensen A, Skakkebæk NE, Rajpert-De Meyts E, Almstrup K. British journal of cancer. 2014;110:668-78. PubMed: 24292451 PMC: PMC3915112

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