CD20 Antibody (clone ABT-CD20)
Catalog Number: LS-C744463
2 sizes / from $274.00
Antibody: Mouse Monoclonal
Applications: Immunohistochemistry (general)
Reactivity: Human
Format: Liquid
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
PathPlus™ CD20 Antibody (clone IGEL/1497R)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$536.00each
Catalog Number: LS-B16234-100
Catalog Number: LS-B16234
For bulk orders or custom formulations:
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- Description
- CD20 antibody LS-B16234 is an unconjugated rabbit recombinant monoclonal antibody to human CD20. Validated for Flow and IHC.
- Application
- FC, IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- B-lymphocyte antigen CD20 | B1 | Bp35 | CD20 | CD20 antigen | CD20 receptor | LEU-16 | CVID5 | MS4A1
- Recommended Dilution: FC
- 0.5 - 1 µg/10E6 cells
- Recommended Dilution: IHC-P
- 1:100
- UniProt Number
- P11836
- NCBI GenBank
- NM_021950 | NP_690605.1
- SwissProt
- P11836
Target
- Target
- CD20
- Antigen Species
- Human
- Specificity
- Recognizes a protein of 30-33 kDa , which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin's disease, particularly of lymphocyte predominant type.
- Epitope
- Recognizes a protein of 30-33 kDa , which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin's disease, particularly of lymphocyte predominant type.
- Gene Name
- MS4A1
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- IGEL/1497R
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human MS4A1 protein. Antigen Molecular Weight: 33-37 kDa
- Immunogen Type
- Full-Length Recombinant Protein
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Animal Free
- No
- Carrier-Free
- No
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS
