Formalin-fixed, paraffin-embedded human Brain stained with Neurofilament Mouse Recombinant Monoclonal Antibody (rNF421).
NEFH / NF-H Antibody (clone rNF421)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Recombinant Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751293-20
Catalog Number: LS-C751293
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- Description
- NF-H antibody LS-C751293 is an unconjugated mouse recombinant monoclonal antibody to human NF-H (NEFH). Validated for Flow, IHC and WB.
- Application
- FC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- 200 kDa neurofilament protein | KIAA0845 | NFH | NF-H | NEFH
- Recommended Dilution: FC
- 0.5 - 1 µg/10E6 cells
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- Recommended Dilution: WB
- 1 - 2 µg/ml
- UniProt Number
- P12036
- NCBI GenBank
- NM_021076 | NP_066554.2
- SwissProt
- P12036
Target
- Target
- Human NEFH / NF-H
- Antigen Species
- Human
- Epitope
- This MAb reacts with a 200 kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
- Gene Name
- NEFH
Antibody
- Host Species
- Mouse
- Clonality
- Recombinant Monoclonal
- Clone
- rNF421
- Isotype
- IgG1
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human NEFH protein. Antigen Molecular Weight: 200 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS