LSBio
Monocytes, Macrophages Antibody (clone MOMA-2, Biotin)

Monocytes, Macrophages Antibody (clone MOMA-2, Biotin)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Frozen
Reactivity:Mouse
Format:Lyophilized
See all Monocytes, Macrophages antibodies →
$630.00each
Catalog Number: LS-C96374-100

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Overview

Description
Monocytes, Macrophages antibody LS-C96374 is a biotin-conjugated rat monoclonal antibody to mouse Monocytes, Macrophages. Validated for IHC. Cited in 2 publications.
Application
IHC, IHC-F
Reactivity
Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Recommended Dilution: IHC-F
1:3000

Target

Target
Monocytes, Macrophages
Epitope
The antigen is a (glyco-)protein of 140kDa m.w. which is located within the cytoplasm and on the cell surface. The epitope has not been further characterized. Antigen distribution: Isolated cells: In the cytospin preparation of thioglycollate stimulated peritoneal exudate cells MOMA-2 detects an antigen as distinct cytoplasmic spots. MOMA-2 detects monocytes of the peripheral blood and a subpopulation of bone marrow cells Tissue sections MOMA-2 detects typical tissue macrophages as does the anti F4/80-specific clone BM8 (pan macrophage marker). However, different staining patterns are visible as shown below. The most predominant difference can be observed in T-cell areas and follicles of peripheral lymphoid organs where the anti F4/80 clone BM8 is negative. Specificity: Mouse: monocytes and macrophages. Other species: not tested.

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
MOMA-2

Immunogen

Immunogen
Mouse Lymph node stroma

Format

Conjugate/Label
Biotin
Format
Lyophilized
Formulation
Lyophilized from PBS pH 7.2, 5mg/ml BSA, 0.1% sodium azide
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C.
Recommended Storage Buffer
PBS

The malnutrition-related increase in early visceralization of Leishmania donovani is associated with a reduced number of lymph node phagocytes and altered conduit system flow. Ibrahim MK, Barnes JL, Anstead GM, Jimenez F, Travi BL, Peniche AG, Osorio EY, Ahuja SS, Melby PC. PLoS neglected tropical diseases. 2013;7:e2329.

PubMed: 23967356 · PMC: PMC3744437

Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection. Ibrahim MK, Barnes JL, Osorio EY, Anstead GM, Jimenez F, Osterholzer JJ, Travi BL, Ahuja SS, White AC Jr, Melby PC. Infection and immunity. 2014;82:3098-112.

PubMed: 24818662 · PMC: PMC4136237

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