LSBio
Monocytes, Macrophages Antibody (clone ER-HR3)

Monocytes, Macrophages Antibody (clone ER-HR3)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Mouse
Format:Lyophilized
See all Monocytes, Macrophages antibodies →
$768.00each
Catalog Number: LS-C96359-500

For bulk orders or custom formulations:

Request a Quote

Overview

Description
Monocytes, Macrophages antibody LS-C96359 is an unconjugated rat monoclonal antibody to mouse Monocytes, Macrophages. Validated for IHC.
Application
IHC, IHC-P
Reactivity
Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Recommended Dilution: IHC-P
1:100

Target

Target
Monocytes, Macrophages
Epitope
The antigen is found on mouse monocytes and a subset of macrophages. The epitope has not been further characterized. Antigen distribution: Isolated cells: The antigen is found on up to 70% of circulating monocytes; all other leukocytes are ER-HR 3 negative. It is also found on a subpopulation (about 30%) of bone marrow cells, mainly consisting of myeloid cells. Tissue sections: In the adult mouse, the antigen is found on distinct subpopulations of resident tissue macrophages in various organs. It is found on a subpopulation of the splenic red pulp macrophages, in the mesenteric lymphoid paracortex, interfollicular areas of Peyer's patches and bone marrow. Epidermal Langerhans cells also express the antigen, whereas macrophages in the connective tissue of the dermis and the gastrointestinal tract only scarcely express the ER-HR 3 related antigen. In the kidney, ER-HR 3 positive macrophages belong to the type 2 interstitial cells in the outer medulla which are negative with BM 8. Distinct ER-HR 3 positive macrophage subpopulations are found in various embryological organs where haematopoietic islands occur, and where they are closely associated with erythrocyte precursor cells. Specificity: Mouse: subpopulation of mature macrophages. Other species: not tested

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
ER-HR3
Isotype
IgG2c

Immunogen

Immunogen
Adherent bone marrow cells
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.