LSBio
Monoclonal Rat anti-Human ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI-GoH3, IHC, IF)

Monoclonal Rat anti-Human ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI-GoH3, IHC, IF)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Flow Cytometry, Immunofluorescence, Immunohistochemistry, Frozen, Immunoprecipitation
Reactivity:Human
Format:Liquid
See all Human ITGA6/Integrin Alpha 6/CD49f antibodies →
$286.00each
Catalog Number: LS-C45280-0.1

For bulk orders or custom formulations:

Request a Quote

Overview

Description
CD49f antibody LS-C45280 is an unconjugated rat monoclonal antibody to human CD49f (ITGA6 / Integrin Alpha 6). Validated for Flow, IF, IHC and IP.
Application
FC, IF, IHC-F, IP
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD49f | CD49f antigen | Integrin alpha6B | Integrin, alpha 6 | Integrin alpha-6 precursor | VLA-6 | Integrin alpha-6 | ITGA6 | ITGA6B
UniProt Number
P23229
SwissProt
P23229

Target

Target
Human ITGA6/Integrin Alpha 6/CD49f
Antigen Species
Human
Epitope
Recognizes the CD49f-antigen, (VLA-6 alpha-chain). CD49f can form distinct complexes with either the CD29-antigen (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology this Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytiotrophoblasts. Platelet VLA-6 functions as a laminin receptor. This clone has been reported to inhibit platelet adhesion to laminin.
Gene Name
ITGA6

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
NKI-GoH3
Isotype
IgG2a

Immunogen

Immunogen
BALB/c mouse mammary tumor cells
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.