LSBio
ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI-GoH3, RPE)

ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI-GoH3, RPE)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Flow Cytometry
Reactivity:Human
Format:Lyophilized
See all Human ITGA6/Integrin Alpha 6/CD49f antibodies →
$413.00each
Catalog Number: LS-C45281-100

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Overview

Description
CD49f antibody LS-C45281 is an RPE-conjugated rat monoclonal antibody to human CD49f (ITGA6 / Integrin Alpha 6). Validated for Flow.
Application
FC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD49f | CD49f antigen | Integrin alpha6B | Integrin, alpha 6 | Integrin alpha-6 precursor | VLA-6 | Integrin alpha-6 | ITGA6 | ITGA6B
Recommended Dilution: FC
1:1 - 1:5
UniProt Number
P23229
NCBI GenBank
NM_000210 | NP_000201.2
SwissProt
P23229

Target

Target
Human ITGA6/Integrin Alpha 6/CD49f
Antigen Species
Human
Epitope
Recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology the monoclonal Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. XXX recommend the use of MCA699XZ for this purpose.
Gene Name
ITGA6

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
NKI-GoH3
Isotype
IgG2a

Immunogen

Immunogen
BALB/c mouse mammary tumor cells
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Phycoerythrin
Format
Lyophilized
Formulation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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