LSBio
Monoclonal Mouse anti-Human SIGLEC7 / CD328 Antibody (clone S7.7, FITC)

Human peripheral blood lymphocytes stained with Mouse anti-Human Siglec-7: FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.

Monoclonal Mouse anti-Human SIGLEC7 / CD328 Antibody (clone S7.7, FITC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry
Reactivity:Human
Format:Liquid
See all Human SIGLEC7 / CD328 antibodies →
$335.00each
Catalog Number: LS-C187562-0.1

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Overview

Description
CD328 antibody LS-C187562 is an FITC-conjugated mouse monoclonal antibody to human CD328 (SIGLEC7). Validated for Flow.
Application
FC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
AIRM-1 | AIRM1 | CD328 antigen | CDw328 | CD328 | D-siglec | QA79 | SIGLEC-7 | SIGLEC7 | QA79 membrane protein
UniProt Number
Q9Y286
NCBI GenBank
NM_014385 | NP_055200.1
SwissProt
Q9Y286

Target

Target
Human SIGLEC7 / CD328
Antigen Species
Human
Epitope
Recognizes human Sialic acid-binding Ig-like lectin 7, otherwise known as CD328, a putative adhesion molecule and member of the Ig superfamily, predominantly expressed by both resting and activated natural killer (NK) cells, and also at lower levels by monocytes, granulocytes, monocyte-derived macrophages and dendritic cells, and a small population of CD8+ memory T cells. Classified as a CD33-related Siglec, Siglec-7 preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid, and acts as a novel inhibitory receptor for NK cells, mediating the inhibition of NK cell cytotoxicity, and implicated in the regulation of NK cell and T cell activation, and hematopoiesis. Clone S7.7 is a blocking antibody see for details, and has been shown to recognize Siglec-7 in Rhesus monkey see for details.
Gene Name
SIGLEC7

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
S7.7
Isotype
IgG1

Immunogen

Immunogen
Siglec-7 3T3 transfected cells.
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Fluorescein Isothiocyanate
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide, 1% BSA
Concentration
0.1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.