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Monoclonal Mouse anti-Human SELL / L-Selectin / CD62L Antibody (clone FMC46, RPE)

Monoclonal Mouse anti-Human SELL / L-Selectin / CD62L Antibody (clone FMC46, RPE)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry
Reactivity:Human
Format:Lyophilized
See all Human SELL / L-Selectin / CD62L antibodies →
$413.00each
Catalog Number: LS-C43270-100

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Overview

Description
CD62L antibody LS-C43270 is an RPE-conjugated mouse monoclonal antibody to human CD62L (SELL / L-Selectin). Validated for Flow.
Application
FC
Reactivity
Hu
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD62L | CD62L antigen | LAM-1 | LAM1 | LECAM1 | LEU8 | Leukocyte adhesion molecule 1 | Lyam-1 | LSEL | gp90-MEL | HLHRc | PLNHR | L-selectin | Leu-8 | Selectin L | SELL | LNHR | LYAM1 | Lymph node homing receptor | Lymphocyte adhesion molecule 1 | TQ1 | Pln homing receptor | CD26L
Recommended Dilution: FC
1:1
NCBI GenBank
NM_000655

Target

Target
Human SELL / L-Selectin / CD62L
Antigen Species
Hu
Epitope
Recognizes human CD62L, also known a L-selectin, a 74-95kD member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of na-ve lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.

Antibody

Host Species
Ms
Clonality
Monoclonal
Clone
FMC46
Isotype
IgG2b

Immunogen

Immunogen
PHA stimulated lymphoblasts.

Format

Conjugate/Label
PE
Format
Lyophilized
Formulation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Preservative
Yes
Purification Method
Prot G

Storage & Handling

Storage Conditions
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.