Monoclonal Rat anti-Mouse CD90.2 (Mouse) Antibody (clone 30H12, AF647)
Catalog Number: LS-C810655
2 sizes / from $259.00
Antibody: Rat Monoclonal
Applications: Flow Cytometry
Reactivity: Mouse
Format: Liquid
Staining of frozen Human Tonsil stained with Mouse anti Human CD206.
Monoclonal Mouse anti-Human Mannose Receptor / CD206 Antibody (clone 7-450, IHC)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunohistochemistry, Frozen |
| Reactivity: | Human |
| Format: | Liquid |
$286.00each
Catalog Number: LS-C58102-0.1
Catalog Number: LS-C58102
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- Description
- CD206 antibody LS-C58102 is an unconjugated mouse monoclonal antibody to human CD206 (Mannose Receptor). Validated for IHC.
- Application
- IHC-F
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- BA541I19.1 | CLEC13D | CD206 | CD206 antigen | Macrophage mannose receptor 1 | Mannose Receptor | Macrophage mannose receptor | MMR | Mannose receptor, C type 1 | MRC1L1 | CLEC13DL | MRC1
- Recommended Dilution: IHC-F
- 1:50 - 1:500
- UniProt Number
- P22897
- NCBI GenBank
- NM_002438 | NP_002429.1
- SwissProt
- P22897
Target
- Target
- Human Mannose Receptor / CD206
- Antigen Species
- Human
- Epitope
- Specific for human CD206, otherwise known as macrophage mannose receptor (MMR), a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites.
- Gene Name
- MRC1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 7-450
- Isotype
- IgG2a
Immunogen
- Immunogen
- Monocyte-derived dendritic cells
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS
