LSBio
IHC-plus™ Mannose Receptor / CD206 Antibody (clone 5C11)

Anti-CD206 antibody IHC of human lung, macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ Mannose Receptor / CD206 Antibody (clone 5C11)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
See all Mannose Receptor / CD206 antibodies →
$470.00each
Catalog Number: LS-B5474-50

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Overview

Description
CD206 antibody LS-B5474 is an unconjugated mouse monoclonal antibody to human CD206 (Mannose Receptor). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
BA541I19.1 | CLEC13D | CD206 | CD206 antigen | Macrophage mannose receptor 1 | Mannose Receptor | Macrophage mannose receptor | MMR | Mannose receptor, C type 1 | MRC1L1 | CLEC13DL | MRC1
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
1:500 - 1:1000
UniProt Number
P22897
SwissProt
P22897

Target

Target
Mannose Receptor / CD206
Antigen Species
Human
Specificity
Human MRC1
Epitope
Human MRC1
Gene Name
MRC1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
5C11
Light Chain
Kappa Light Chain
Origin Species
Human

Immunogen

Immunogen
MRC1 (NP_002429, 22 aa ~ 131 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4
Animal Free
No
Carrier-Free
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

CD163 macrophage and erythrocyte contents in aspirated deep vein thrombus are associated with the time after onset: a pilot study. Eiji Furukoji , Toshihiro Gi , Atsushi Yamashita, Sayaka Moriguchi-Goto, Mio Kojima, Chihiro Sugita, Tatefumi Sakae, Yuichiro Sato, Toshinori Hirai, Yujiro Asada. Thrombosis journal. 2016 November;14:46.

PubMed: 27895532 · PMC: PMC5120412


Lipid droplet-dependent fatty acid metabolism controls the immune suppressive phenotype of tumor-associated macrophages. Hao Wu, Yijie Han, Yasmina Rodriguez Sillke, Hongzhang Deng, Sophiya Siddiqui, Christoph Treese, Franziska Schmidt, Marie Friedrich, Jacqueline Keye, Jiajia Wan, Yue Qin, Anja A Kühl, Zhihai Qin, Britta Siegmund, Rainer Glauben. EMBO molecular medicine. 2019 November;11:e10698.

PubMed: 31602788 · PMC: PMC6835560

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