LSBio
Monoclonal Mouse anti-Human MAdCAM-1 Antibody (clone 314G8, IHC)

Monoclonal Mouse anti-Human MAdCAM-1 Antibody (clone 314G8, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen
Reactivity:Human
Format:Liquid
See all Human MAdCAM-1 antibodies →
$392.00each
Catalog Number: LS-C44686-0.2

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Overview

Description
MAdCAM-1 antibody LS-C44686 is an unconjugated mouse monoclonal antibody to human MAdCAM-1. Validated for ELISA, Flow and IHC.
Application
ELISA, FC, IHC, IHC-F
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
HMAdCAM-1 | MACAM1 | MAdCAM-1 | MADCAM1
Recommended Dilution: FC
1:10 - 1:100
UniProt Number
Q13477
SwissProt
Q13477

Target

Target
Human MAdCAM-1
Antigen Species
Human
Epitope
Recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1) a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyers patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone Reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7.
Gene Name
MADCAM1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
314G8
Isotype
IgG1

Immunogen

Immunogen
Recombinant soluble MAdCAM-1-fc fusion protein
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.