Anti-IGF1 Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.

Monoclonal Mouse anti-Human IGF1R / IGF1 Receptor Antibody (clone 1H7, RPE)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry
Reactivity:	Human
Format:	Lyophilized

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$413.00each

Catalog Number: LS-C44713-100

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Overview

Description: IGF1 Receptor antibody LS-C44713 is an RPE-conjugated mouse monoclonal antibody to human IGF1 Receptor (IGF1R). Validated for Flow.
Application: FC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD221 antigen | CD221 | IGF1R | IGF1 Receptor | IGFR | IGF-I receptor | Soluble IGF1R variant 1 | Soluble IGF1R variant 2 | Type 1 IGF receptor | IGFIR | JTK13
Recommended Dilution: FC: 1:1
UniProt Number: P08069
NCBI GenBank: NM_000875 | NP_000866.1
SwissProt: P08069

Target

Target: Human IGF1R / IGF1 Receptor
Antigen Species: Human
Epitope: Recognizes human CD221, a 155kD receptor tyrosine kinase, also known as Insulin-like growth factor I receptor (IGF-I Receptor). CD221 is composed of two extracellular alpha-subunits and two transmembrane beta-subunits. Recognizes an epitope in the alpha subunits of CD221, demonstrated by Western blotting. CD221 is expressed in a range of tissues, including kidney, liver, placenta, mammary gland, brain, ovary and skin. The ligands for CD221 include IGF-I and IGF-II, which bind to CD221 and activate tyrosine kinase activity, resulting in phosphorylation of several intracellular signalling proteins. Clone 1H7 is reported to partially block binding of IGF-I and IGF-II to CD221
Gene Name: IGF1R

Antibody

Host Species: Mouse
Clonality: Monoclonal
Clone: 1H7
Isotype: IgG1

Format

Conjugate/Label: Phycoerythrin
Format: Lyophilized
Formulation: PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Preservative: Yes
Purification Method: Protein G Affinity

Storage & Handling

Storage Conditions: Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS