Anti-IGF1 Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.

IHC-plus™ IGF1R / IGF1 Receptor Antibody (clone 1H7)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:	Human
Format:	Liquid

See all IGF1R / IGF1 Receptor antibodies â†’

$383.00each

Catalog Number: LS-B2613-50

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Overview

Description: IGF1 Receptor antibody LS-B2613 is an unconjugated mouse monoclonal antibody to human IGF1 Receptor (IGF1R). Validated for Flow, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Application: FC, IHC, IHC-P, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD221 antigen | CD221 | IGF1R | IGF1 Receptor | IGFR | IGF-I receptor | Soluble IGF1R variant 1 | Soluble IGF1R variant 2 | Type 1 IGF receptor | IGFIR | JTK13
Recommended Dilution: FC: 1:10
Recommended Dilution: IHC-P: 10 µg/ml
UniProt Number: P08069
NCBI GenBank: NM_000875 | NP_000866.1
SwissProt: P08069

Target

Target: IGF1R / IGF1 Receptor
Antigen Species: Human
Specificity: Recognizes human CD221, a 155kD receptor tyrosine kinase, also known as Insulin-like growth factor I receptor (IGF-I Receptor). CD221 is composed of two extracellular alpha-subunits and two transmembrane beta-subunits. Recognizes an epitope in the alpha subunits of CD221, demonstrated by Western blotting. CD221 is expressed in a range of tissues, including kidney, liver, placenta, mammary gland, brain, ovary and skin. The ligands for CD221 include IGF-I and IGF-II, which bind to CD221 and activate tyrosine kinase activity, resulting in phosphorylation of several intracellular signalling proteins. Clone 1H7 is reported to partially block binding of IGF-I and IGF-II to CD221
Epitope: Recognizes human CD221, a 155kD receptor tyrosine kinase, also known as Insulin-like growth factor I receptor (IGF-I Receptor). CD221 is composed of two extracellular alpha-subunits and two transmembrane beta-subunits. Recognizes an epitope in the alpha subunits of CD221, demonstrated by Western blotting. CD221 is expressed in a range of tissues, including kidney, liver, placenta, mammary gland, brain, ovary and skin. The ligands for CD221 include IGF-I and IGF-II, which bind to CD221 and activate tyrosine kinase activity, resulting in phosphorylation of several intracellular signalling proteins. Clone 1H7 is reported to partially block binding of IGF-I and IGF-II to CD221.
Gene Name: IGF1R

Antibody

Host Species: Mouse
Clonality: Monoclonal
Clone: 1H7

Format

Conjugate/Label: Unconjugated
Format: Liquid
Formulation: PBS, 0.09% Sodium Azide
Concentration: 1 mg/mL
Animal Free: No
Carrier-Free: Yes
Preservative: Yes
Purification Method: Protein G Affinity

Storage & Handling

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS