Monoclonal Rat anti-Mouse CD90.2 (Mouse) Antibody (clone 30H12, AF647)
Catalog Number: LS-C810655
2 sizes / from $259.00
Antibody: Rat Monoclonal
Applications: Flow Cytometry
Reactivity: Mouse
Format: Liquid
Monoclonal Mouse anti-Human GREM1 / Gremlin-1 Antibody (clone 4C2, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Lyophilized |
$647.00each
Catalog Number: LS-C125371-100
Catalog Number: LS-C125371
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- Description
- Gremlin-1 antibody LS-C125371 is an unconjugated mouse monoclonal antibody to Gremlin-1 (GREM1) from human. It is reactive with human and mouse. Validated for ELISA and WB. Cited in 1 publication.
- Application
- ELISA, IHC, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CKTSF1B1 | DAN domain family member 2 | DAND2 | DRM | GREM1 | GREMLIN | Gremlin 1-like protein | Increased in high glucose-2 | Gremlin-1 | PIG2 | Proliferation-inducing gene 2 | Gremlin 1 | IHG-2
- UniProt Number
- O60565
- NCBI GenBank
- NM_013372 | NP_037504.1
- SwissProt
- O60565
Target
- Target
- Human GREM1 / Gremlin-1
- Antigen Species
- Human
- Epitope
- Recognizes human Gremlin 1. Cross reactivity with mouse.
- Gene Name
- GREM1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 4C2
- Isotype
- IgG
Immunogen
- Immunogen
- Partial recombinant human Gremlin-1 (75-185) with a GST tag.
- Immunogen Type
- Fusion Protein (e.g., GST, MBP tag)
Format
- Conjugate/Label
- Unconjugated
- Format
- Lyophilized
- Formulation
- Lyophilized PBS, pH 7.4
- Preservative
- No
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C lyophilized. Once reconstituted: Store at -20°C. Aliquot to avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-?B pathway. Chang SH, Mori D, Kobayashi H, Mori Y, Nakamoto H, Okada K, Taniguchi Y, Sugita S, Yano F, Chung UI, Kim-Kaneyama JR, Yanagita M, Economides A, Canalis E, Chen D, Tanaka S, Saito T. Nature communications. 2019 March;10:1442. PubMed: 30926814 PMC: PMC6441020
