LSBio
Monoclonal Mouse anti-Human B cell Antibody (clone FMC7, FITC)

Monoclonal Mouse anti-Human B cell Antibody (clone FMC7, FITC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry
Reactivity:Human
Format:Liquid
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$610.00each
Catalog Number: LS-C45373-1

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Overview

Description
B cell antibody LS-C45373 is an FITC-conjugated mouse monoclonal antibody to human B cell. Validated for Flow.
Application
FC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Recommended Dilution: FC
1:1

Target

Target
Human B cell
Antigen Species
Human
Epitope
Recognizes a glycoprotein antigen of 105kD expressed by B lymphocytes. The FMC7 antigen is expressed by peripheral B lymphocytes, and has been used widely in the study of B cell malignancy. FMC7 has been used extensively to differentiate various types of B cell malignancy. B-CLL is generally considered to be negative for FMC7 expression, but strong staining is seen in many other types of B cell lymphoma, including prolymphocytic leukemia and hairy cell leukemia. The nature of the FMC7 antigen has remained poorly defined following its first description in 1981. The expression pattern closely corresponds to that seen with CD22, but studies have shown that FMC7 does not recognize the CD22 molecule itself. A recent publication by Serke et al has shown Recognizes a conformational epitope on the CD20 molecule, most likely a multimeric complex of CD20.

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
FMC7
Isotype
IgM

Immunogen

Immunogen
HRIK cells - Human B-Lymphoblastoid line.
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Fluorescein Isothiocyanate
Format
Liquid
Formulation
TRIS Buffered Glycine, 0.1% Sodium Azide, 0.2% BSA
Volume
1 Milliliter
Preservative
Yes
Purification Method
Other

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
TRIS Buffered

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.