
Monoclonal Hamster anti-Human ADGRE3 / EMR3 Antibody (clone 3D7)
| Antibody: | Hamster Monoclonal |
| Applications: | Flow Cytometry, Immunoprecipitation |
| Reactivity: | Human |
| Format: | Liquid |
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- Description
- EMR3 antibody LS-C44908 is an unconjugated hamster monoclonal antibody to human EMR3 (ADGRE3). Validated for Flow and IP.
- Application
- FC, IP
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- EGF-like module receptor 3 | EMR3
- Recommended Dilution: FC
- 1:50 - 1:200
- UniProt Number
- Q9BY15
- NCBI GenBank
- NM_032571 | NP_115960.2
- SwissProt
- Q9BY15
Target
- Target
- Human ADGRE3 / EMR3
- Antigen Species
- Human
- Epitope
- Recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56kD member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer. The molecule is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, hematopoietic stem cells and myeloid progenitors. Studies suggest that the EMR3 molecule is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. The exact functions of EMR3 and its ligands have not yet been determined.
- Gene Name
- ADGRE3
Antibody
- Host Species
- Hamster
- Clonality
- Monoclonal
- Clone
- 3D7
- Isotype
- IgG
Immunogen
- Immunogen
- ARHO-EMR3-CD97 (EGF1) transfectants
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS




