LSBio
Macrophage Antibody (clone PM-2K)

IHC of Macrophages antibody. Frozen section of pig spleen.

Macrophage Antibody (clone PM-2K)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Frozen
Reactivity:Human
Format:Lyophilized
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$768.00each
Catalog Number: LS-C96248-100

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Overview

Description
Macrophage antibody LS-C96248 is an unconjugated mouse monoclonal antibody to human Macrophage. Validated for IHC.
Application
IHC, IHC-F
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Mature Macrophage Marker
Recommended Dilution: IHC-F
1:400

Target

Target
Macrophage
Epitope
The antigen of 150kDa m.w. is found in the macrophage cell membrane. The epitope has not been determined. Antigen distribution: Isolated cells: Positive on >90% of alveolar macrophages, and on 10% of adherent peritoneal cells after 1 day culture. Negative on dendritic cells, on freshly isolated blood monocytes or peritoneal cells; and on bone marrow cells including monocytes, myelomonocytic precursors and megakaryocytes. Tissue sections: PM-2K stains most tissue macrophages in lymphoreticular organs such as thymus, spleen, lymph node and tonsil. It is positive on Kupffer cells of the liver, alveolar macrophages and macrophages in the interstitial tissues of the kidney, pancreas and many other organs. In Gaucher's disease multicentric reticulohistiocytosis and malignant histiocytosis proliferating macrophages are positive. In MFH infiltrating macrophages are stained but not tumour cells. Some bone stromal cells but not osteoclast-like multinucleated giant cells are stained in GCT. Microglial cells, osteoclasts and dendritic cells such as Langerhans cells, interdigitating cells and follicular dendritic cells are negative. Specificity: Human: Macrophages. Other: positive on macrophages of cat, dog, pig, bovine and monkey; negative in rabbit, rat, guinea pig, gold hamster, goat, horse.

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
PM-2K

Immunogen

Immunogen
Cultured human peritoneal macrophages
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from PBS pH 7.2, 5mg/ml BSA, and 0.05% Kathon CG
Preservative
No
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.