IHC of Macrophages antibody. Frozen section of rat spleen.

Macrophage Antibody (clone Ki-M2R)

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Antibody:	Mouse Monoclonal
Applications:	Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:	Rat
Format:	Lyophilized

$768.00each

Catalog Number: LS-C96396-100

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Description: Macrophage antibody LS-C96396 is an unconjugated mouse monoclonal antibody to rat Macrophage. Validated for IHC.
Application: IHC, IHC-P
Reactivity: Rt
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: Mature Macrophage Marker
Recommended Dilution: IHC-P: 1:400

Target: Macrophage
Epitope: Ki-M2R recognizes a surface antigen of 45kD molecular weight as a single band under reducing conditions. The epitope has not been further characterized Antigen distribution: Isolated cells: In the bone marrow a minor number of macrophages reveal a strong reactivity whereas granulocytes, erythropoetic cells and megacaryocytes are negative. Immature accessory cells such as dendritic or interdigitating reticulum cells are also negative. Monocytes show a positive reaction when exposed to TPA or foreign material. Tissue sections: Ki-M2R positive cells have been recognised as active phagocytes in serous cavities (peritoneal and pleural macrophages). Liver (Kupffer cells), spleen (macrophages of the red pulp), lymph nodes (macrophages of the pulp and sinus, tingible body macrophages), lung (approx. 50% of alveolar macrophages) and connective tissue (histiocytes) are positively stained. Plasma cells (excluding stimulated monocytes) as well as sinus lining cells are negative. Specificity: Rat: mature macrophages. Other species: not tested