LSBio
LPIN3 / Lipin-3 Antibody (aa428-529)

LPIN3 / Lipin-3 Antibody (aa428-529)

Primary AntibodyLSBio Guarantee
Antibody:Goat Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunocytochemistry, Western Blot
Reactivity:Mouse
Format:Lyophilized
See all Mouse LPIN3 / Lipin-3 antibodies →
$914.00each
Catalog Number: LS-C37207-100

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Overview

Description
Lipin-3 antibody LS-C37207 is an unconjugated goat polyclonal antibody to mouse Lipin-3 (LPIN3) (aa428-529). Validated for ELISA, ICC and WB. Cited in 3 publications.
Application
ELISA, ICC, WB
Reactivity
Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
DJ620E11.2 | DJ450M14.2 | Lipin-3 | Lipin 3 | Lipin 3-like | Lipin-3-like | LPIN3 | SMP2 | DJ450M14.3 | LIPN3L
Recommended Dilution: ELISA
0.5 - 1 ug/ml
UniProt Number
Q9BQK8
NCBI GenBank
NP_075047.1
SwissProt
Q9BQK8

Target

Target
Mouse LPIN3 / Lipin-3
Antigen Species
Mouse
Epitope
Selected for its ability to recognize Lipin 3 in the applications listed. In direct ELISAs and Western Blots, this antibody shows ~50% cross-reactivity with rhLipin 3 and less than 5% cross-reactivity with rhLipin 1 and rhLipin 2.
Gene Name
LPIN3

Antibody

Host Species
Goat
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
E. coli-derived recombinant mouse Lipin 3 (aa 428-529).
Immunogen Type
Recombinant Protein Fragment

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from PBS, pH 7.4, 5% Trehalose
Preservative
No
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at -20°C lyophilized. Once reconstituted: Store at -20°C. Aliquot to avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Lipin-1 and lipin-3 together determine adiposity in vivo. Csaki LS, Dwyer JR, Li X, Nguyen MH, Dewald J, Brindley DN, Lusis AJ, Yoshinaga Y, de Jong P, Fong L, Young SG, Reue K. Molecular metabolism. 2014;3:145-54.

PubMed: 24634820


Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum. Dwyer JR, Donkor J, Zhang P, Csaki LS, Vergnes L, Lee JM, Dewald J, Brindley DN, Atti E, Tetradis S, Yoshinaga Y, De Jong PJ, Fong LG, Young SG, Reue K. Proceedings of the National Academy of Sciences of the United States of America. 2012;109:E2486-95.

PubMed: 22908270


Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis. Zhang P, Csaki LS, Ronquillo E, Baufeld LJ, Lin JY, Gutierrez A, Dwyer JR, Brindley DN, Fong LG, Tontonoz P, Young SG, Reue K. The Journal of clinical investigation. 2019 January;129:281-295.

PubMed: 30507612 · PMC: PMC6307960

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