KLRK1 / CD314 / NKG2D Antibody (clone 1D11, FITC)

Name: KLRK1 / CD314 / NKG2D Antibody (clone 1D11, FITC)
Brand: LSBio
SKU: LS-C44805-0.1
Price: 335 USD
Availability: InStock

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$335.00each

Catalog Number: LS-C44805-0.1

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Description: NKG2D antibody LS-C44805 is an FITC-conjugated mouse monoclonal antibody to human NKG2D (KLRK1 / CD314). Validated for Flow.
Application: FC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: D12S2489E | CD314 antigen | KLR | KLRK1 | NK cell receptor D | NKG2D | NKG2-D | NKG2-D-activating NK receptor | CD314
Recommended Dilution: FC: 1:1 - 1:10
UniProt Number: P26718
NCBI GenBank: NM_007360 | NP_031386.2
SwissProt: P26718

Target: Human KLRK1 / CD314 / NKG2D
Antigen Species: Human
Epitope: Specific for CD314 also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6). XXX recommend the use of MCA2405EL for such studies.
Gene Name: KLRC4-KLRK1|KLRK1

Storage Conditions: Store at 4°C or at -20°C. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS

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