Formalin-fixed, paraffin-embedded Human Tonsil stained with Kappa Light Chain Rabbit Recombinant Monoclonal (KLC2289R).

Kappa Light Chain Antibody (clone KLC2289R)

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Antibody:	Rabbit Recombinant Monoclonal
Applications:	Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

$379.00each

Catalog Number: LS-C751206-20

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Description: Kappa Light Chain antibody LS-C751206 is an unconjugated rabbit recombinant monoclonal antibody to human Kappa Light Chain. Validated for IHC.
Application: IHC, IHC-P
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: IGKCD | Immunoglobulin kappa constant | IGKC | Kappa Light Chain | HCAK1 | Km
Recommended Dilution: IHC-P: 0.5 - 1 µg/ml
UniProt Number: P01834
SwissProt: P01834

Target: Human Kappa Light Chain
Antigen Species: Human
Epitope: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.