ITGB3 / Integrin Beta 3 / CD61 Antibody (clone HM beta 3.1, RPE)
Primary AntibodyLSBio Guarantee
| Antibody: | Hamster Monoclonal |
| Applications: | Flow Cytometry |
| Reactivity: | Mouse |
| Format: | Lyophilized |
$413.00each
Catalog Number: LS-C44646-100
Catalog Number: LS-C44646
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- Description
- CD61 antibody LS-C44646 is an RPE-conjugated hamster monoclonal antibody to mouse CD61 (ITGB3 / Integrin Beta 3). Validated for Flow.
- Application
- FC
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- BDPLT2 | CD61 antigen | GT | gp3A | CD61 | GPIIIa | Integrin beta-3 | ITGB3
- Recommended Dilution: FC
- 1:1 - 1:10
- UniProt Number
- P05106
- NCBI GenBank
- NM_000212 | NP_000203.2
- SwissProt
- P05106
Target
- Target
- Mouse ITGB3 / Integrin Beta 3 / CD61
- Antigen Species
- Mouse
- Epitope
- Recognizes the murine integrin beta 3 subunit (CD61), a 90kD type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.
- Gene Name
- ITGB3
Antibody
- Host Species
- Hamster
- Clonality
- Monoclonal
- Clone
- HM beta 3.1
- Isotype
- IgG
Immunogen
- Immunogen
- Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4
- Immunogen Type
- Native Protein (Purified from Natural Source)
Format
- Conjugate/Label
- Phycoerythrin
- Format
- Lyophilized
- Formulation
- PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C. Do not freeze. Store untiluted. Protect from light.
- Recommended Storage Buffer
- PBS