ITGB3 / Integrin Beta 3 / CD61 Antibody (clone HM beta 3.1, FITC)
Primary AntibodyLSBio Guarantee
| Antibody: | Hamster Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general) |
| Reactivity: | Mouse |
| Format: | Liquid |
$335.00each
Catalog Number: LS-C44643-0.1
Catalog Number: LS-C44643
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- Description
- CD61 antibody LS-C44643 is an FITC-conjugated hamster monoclonal antibody to mouse CD61 (ITGB3 / Integrin Beta 3). Validated for Flow.
- Application
- FC, IHC
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- BDPLT2 | CD61 antigen | GT | gp3A | CD61 | GPIIIa | Integrin beta-3 | ITGB3
- Recommended Dilution: FC
- 1:1 - 1:10
- UniProt Number
- P05106
- NCBI GenBank
- NM_000212 | NP_000203.2
- SwissProt
- P05106
Target
- Target
- Mouse ITGB3 / Integrin Beta 3 / CD61
- Antigen Species
- Mouse
- Epitope
- Recognizes the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.
- Gene Name
- ITGB3
Antibody
- Host Species
- Hamster
- Clonality
- Monoclonal
- Clone
- HM beta 3.1
- Isotype
- IgG
Immunogen
- Immunogen
- Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4
- Immunogen Type
- Native Protein (Purified from Natural Source)
Format
- Conjugate/Label
- Fluorescein Isothiocyanate
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide, 1% BSA
- Concentration
- 0.1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light.
- Recommended Storage Buffer
- PBS