LSBio
IHC-plus™ TNFSF11 / RANKL / TRANCE Antibody

Anti-RANKL antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ TNFSF11 / RANKL / TRANCE Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
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$470.00each
Catalog Number: LS-B1425-0.05

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Overview

Description
TRANCE antibody LS-B1425 is an unconjugated rabbit polyclonal antibody to TRANCE (TNFSF11 / RANKL) from human. It is reactive with human, mouse and rat. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CD254 | CD254 antigen | HRANKL2 | OPTB2 | TRANCE | TNFSF11 | ODF | OPGL | SOdf | Osteoprotegerin ligand | RANKL
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
0.25 - 0.5 µg/ml
UniProt Number
O14788
SwissProt
O14788

Target

Target
TNFSF11 / RANKL / TRANCE
Antigen Species
Human
Gene Name
TNFSF11

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A 14 AA synthetic peptide near the center of human sRANK-L. The immunogen is located within aa 140-190 of sRANK Ligand.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS containing 0.02% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Recommended Storage Buffer
PBS

Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation. Wang C, Shen J, Yukata K, Inzana JA, O'Keefe RJ, Awad HA, Hilton MJ. Bone. Apr;73:77-89.

PubMed: 25527421 · PMC: PMC4336841


Granulomatous Inflammation and Hypercalcemia in Patients With Severe Systemic Oxalosis. Peggy Perrin, Jérome Olagne, Arnaud Delbello, Stanislas Bataille, Laurent Mesnard, Claire Borni, Bruno Moulin, Sophie Caillard. Kidney international reports. 2022 February;7:343-349.

PubMed: 35155875 · PMC: PMC8820998

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