Polyclonal Chicken GFP Antibody (clone IQGFP6 Polyclonal, WB)
Catalog Number: LS-C827997-50
50 µL (1 mg/mL) / $492.00
Antibody: Chicken Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Format: Liquid
Anti-TJP2 / ZO-2 antibody IHC of human placenta, intermediate trophoblasts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
IHC-plus™ Polyclonal Rabbit anti-Human TJP2 / ZO2 / ZO-2 Antibody (C-Terminus, IHC, IF, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Dog, Human, Mouse, Rat |
| Format: | Liquid |
$495.00each
Catalog Number: LS-B2185-50
Catalog Number: LS-B2185
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- ZO-2 antibody LS-B2185 is an unconjugated rabbit polyclonal antibody to ZO-2 (TJP2 / ZO2) (C-Terminus) from human. It is reactive with human, mouse, rat and other species. Validated for IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
- Application
- IF, IHC, IHC-P, WB
- Reactivity
- Can, Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- C9DUPq21.11 | DUP9q21.11 | DFNA51 | TJP2 | ZO-2 | Zona occludens 2 | Zonula occludens protein 2 | Tight junction protein 2 | Tight junction protein ZO-2 | ZO2 | X104 | Zona occludens protein 2
- Recommended Dilution: IF/ICC
- 2.5 µg/ml
- Recommended Dilution: IHC-P
- 5 - 10 µg/ml
- Recommended Dilution: WB
- 1 - 3 µg/ml
- UniProt Number
- Q9UDY2
- NCBI GenBank
- NM_004817 | NP_004808.2
- SwissProt
- Q9UDY2
Target
- Target
- TJP2 / ZO2 / ZO-2
- Antigen Species
- Human
- Specificity
- Recognizes the ~130-160kD human ZO-2 protein, isoforms A or C. A band of unknown origin lower than 75kD may be observed in certain lysates.
- Epitope
- Recognizes the ~130-160kD human ZO-2 protein, isoforms A or C. A band of unknown origin lower than 75kD may be observed in certain lysates.
- Gene Name
- TJP2
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide derived from the C-Terminus of human or canine ZO-2.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.09% Sodium Azide
- Concentration
- 0.25 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Mutations in TJP2 cause progressive cholestatic liver disease. Sambrotta M, Strautnieks S, Papouli E, Rushton P, Clark BE, Parry DA, Logan CV, Newbury LJ, Kamath BM, Ling S, Grammatikopoulos T, Wagner BE, Magee JC, Sokol RJ, Mieli-Vergani G, Smith JD, Johnson CA, McClean P, Simpson MA, Knisely AS, Bull LN, Thompson RJ. Nature genetics. Apr;46:326-8.
PubMed: 24614073 · PMC: PMC4061468
TJP2 hepatobiliary disorders: Novel variants and clinical diversity. Jing Zhang, Lang-Li Liu, Jing-Yu Gong, Chen-Zhi Hao, Yi-Ling Qiu, Yi Lu, Jia-Yan Feng, Jia-Qi Li, Zhong-Die Li, Meng-Xuan Wang, Qing-He Xing, A S Knisely, Jian-She Wang. Human mutation. 2020 Feburary;41:502-511.
PubMed: 31696999
Low-GGT intrahepatic cholestasis associated with biallelic USP53 variants: Clinical, histological and ultrastructural characterization. Jing Zhang, Ye Yang, Jing-Yu Gong, Li-Ting Li, Jia-Qi Li, Mei-Hong Zhang, Yi Lu, Xin-Bao Xie, Yu-Ren Hong, Zhang Yu, A S Knisely, Jian-She Wang. Liver international : official journal of the International Association for the Study of the Liver. 2020 May;40:1142-1150.
PubMed: 32124521
