LSBio
IHC-plus™ Polyclonal Rabbit anti-Human PTGER4 / EP4 Antibody (N-Terminus, IHC)

Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ Polyclonal Rabbit anti-Human PTGER4 / EP4 Antibody (N-Terminus, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all PTGER4 / EP4 antibodies →
$449.00each
Catalog Number: LS-A3898-50

For bulk orders or custom formulations:

Request a Quote

Overview

Description
EP4 antibody LS-A3898 is an unconjugated rabbit polyclonal antibody to human EP4 (PTGER4) (N-Terminus). Validated for ICC and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Application
IHC
Reactivity
Hu
Predicted Reactivity
Non-Human Primate
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
EP4 | EP4 prostaglandin receptor | EP4R | PGE receptor EP4 subtype | Prostanoid EP4 receptor | Prostaglandin E receptor 4 | PTGER4 | PGE receptor, EP4 subtype | PGE2 receptor EP4 subtype
Recommended Dilution: IHC-P
2.5 µg/ml
UniProt Number
P35408
SwissProt
P35408

Target

Target
PTGER4 / EP4
Antigen Species
Human
Specificity
N-terminus of human PTGER4 / EP4. BLAST analysis of the peptide immunogen showed no homology with other human proteins
Epitope
Human PTGER4 / EP4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
PTGER4

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 14 amino acid peptide from N-Terminus extracellular domain of human PTGER4 / EP4. Percent identity with other species by BLAST analysis: Human (100%); Chimpanzee, Gorilla, Marmoset (93%); Gibbon, Monkey (86%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model. Terada N, Shimizu Y, Kamba T, Inoue T, Maeno A, Kobayashi T, Nakamura E, Kamoto T, Kanaji T, Maruyama T, Mikami Y, Toda Y, Matsuoka T, Okuno Y, Tsujimoto G, Narumiya S, Ogawa O. Cancer research. 2010 Feb;70:1606-15.

PubMed: 20145136


EP4 and Class III ß-Tubulin Expression in Uterine Smooth Muscle Tumors: Implications for Prognosis and Treatment. Reader J, Harper AK, Legesse T, Staats PN, Goloubeva O, Rao GG, Fulton A, Roque DM. Cancers. 2019 October;11:E1590.

PubMed: 31635323 · PMC: PMC6826612


Prostaglandin E Receptor EP4 expression, survival and pattern of recurrence in locally advanced NSCLC. Neha Bhooshan, Paul N Staats, Amy M Fulton, Josephine L Feliciano, Martin J Edelman. Lung cancer (Amsterdam, Netherlands). 2016 November;101:88-91.

PubMed: 27794413 · PMC: PMC7428069

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.