LSBio
IHC-plus™ O3FAR1 / GPR120 Antibody (N-Terminus)

Anti-O3FAR1 / GPR120 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ O3FAR1 / GPR120 Antibody (N-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all O3FAR1 / GPR120 antibodies →
$403.00each
Catalog Number: LS-A2003-50

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Overview

Description
GPR120 antibody LS-A2003 is an unconjugated rabbit polyclonal antibody to human GPR120 (O3FAR1) (N-Terminus). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 4 publications.
Application
IHC
Reactivity
Hu
Predicted Reactivity
Non-Human Primate
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
FFAR4 | Free fatty acid receptor 4 | GT01 | GPR129 | GPR120 | O3FAR1 | PGR4 | BMIQ10
Recommended Dilution: IHC-P
1 µg/ml
UniProt Number
Q5NUL3
SwissProt
Q5NUL3

Target

Target
O3FAR1 / GPR120
Antigen Species
Human
Specificity
Human O3FAR1 / GPR120. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TFE3 (40%).
Epitope
Human O3FAR1 / GPR120. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TFE3 (40%).
Gene Name
FFAR4

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 20 amino acid peptide from N-Terminus extracellular domain of human O3FAR1 / GPR120. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (90%); Bovine (80%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
0.9 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

G protein-coupled receptors in human fat taste perception. Galindo MM, Voigt N, Stein J, van Lengerich J, Raguse JD, Hofmann T, Meyerhof W, Behrens M. Gastroenterology. 2014 Feb;37:123-39.

PubMed: 21868624


CD36- and GPR120-mediated Ca2+ signaling in human taste bud cells mediates differential responses to fatty acids and is altered in obese mice. Ozdener MH, Subramaniam S, Sundaresan S, Sery O, Hashimoto T, Asakawa Y, Besnard P, Abumrad NA, Khan NA. Gastroenterology. Apr;146:995-1005.

PubMed: 24412488 · PMC: PMC3979457


Characterization of duodenal expression and localization of fatty acid-sensing receptors in humans: relationships with body mass index. Little TJ, Isaacs NJ, Young RL, Ott R, Nguyen NQ, Rayner CK, Horowitz M, Feinle-Bisset C. American journal of physiology. Gastrointestinal and liver physiology. 2014;307:G958-67.

PubMed: 25258406


Eicosapentaenoic acid prevents the progression of intracranial aneurysms in rats. Yu Abekura, Isao Ono, Akitsugu Kawashima, Katsumi Takizawa, Hirokazu Koseki, Haruka Miyata, Kampei Shimizu, Mieko Oka, Mika Kushamae, Susumu Miyamoto, Hiroharu Kataoka, Akira Ishii, Tomohiro Aoki. Journal of neuroinflammation. 2020 Apr;17:129.

PubMed: 32331514 · PMC: PMC7181479

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