LSBio
IHC-plus™ Monoclonal Mouse anti-Human VTN / Vitronectin Antibody (IHC, WB)

Anti-Vitronectin antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ Monoclonal Mouse anti-Human VTN / Vitronectin Antibody (IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Bovine, Cat, Dog, Goat, Horse, Human
Format:Liquid
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$556.00each
Catalog Number: LS-B2118-50

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Overview

Description
Vitronectin antibody LS-B2118 is an unconjugated mouse monoclonal antibody to Vitronectin (VTN) from human. It is reactive with human, bovine, cat and other species. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Bov, Can, Fel, Gt, Hr, Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Epibolin | Serum-spreading factor | VNT | VTN | S-protein | Somatomedin B | V75 | VN | Complement S-protein | Serum spreading factor | Vitronectin
Recommended Dilution: ELISA
1:30000
Recommended Dilution: IHC-P
2.5 µg/ml
Recommended Dilution: WB
1:50
UniProt Number
P04004
SwissProt
P04004

Target

Target
VTN / Vitronectin
Antigen Species
Human
Specificity
Recognizes human vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). Species Crossreactivity: feline, canine, goat, bovine and to a lesser extent with equine. Binds nearly as well to native vitronectin as to denatured. Is a potent inhibitor of integrin-mediated cell adhesion to vitronectin and a moderate inhibitor of PAI-1 binding.
Epitope
Recognizes human vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). Species Crossreactivity: feline, canine, goat, bovine and to a lesser extent with equine. Binds nearly as well to native vitronectin as to denatured. Is a potent inhibitor of integrin-mediated cell adhesion to vitronectin and a moderate inhibitor of PAI-1 binding.
Gene Name
VTN

Antibody

Host Species
Mouse
Clonality
Monoclonal
Light Chain
Kappa Light Chain
Origin Species
Human

Immunogen

Immunogen
Human vitronectin purified from plasma by heparin-affinity chromatography.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 15 mM Sodium Azide
Concentration
1.05 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. Nicole Merritt , Keith Garcia , Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas. eLife. 2021 April;10:e62857. PubMed: 33913810 PMC: PMC8143797

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