LSBio
IHC-plus™ Monoclonal Mouse anti-Human SRSF1 / SF2 Antibody (N-Terminus, IHC, IF, WB)

Anti-SF2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ Monoclonal Mouse anti-Human SRSF1 / SF2 Antibody (N-Terminus, IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
See all SRSF1 / SF2 antibodies →
$495.00each
Catalog Number: LS-B2340-50

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Overview

Description
SF2 antibody LS-B2340 is an unconjugated mouse monoclonal antibody to SF2 (SRSF1) (N-Terminus) from human. It is reactive with human, mouse and rat. Validated for IF, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IF, IHC, IHC-P, IP, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Alternative-splicing factor 1 | ASF | SF2 | SF2p33 | SFRS1 | Splicing factor 2 | ASF-1 | SR splicing factor 1 | SRp30a | SRSF1
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
0.5 - 1 µg/ml
UniProt Number
Q07955
SwissProt
Q07955

Target

Target
SRSF1 / SF2
Antigen Species
Human
Specificity
Recognizes the N-terminal portion (aa1-97) of the SF2/ASF protein comprising the RNA-recognition motif (RRM1). Reactivity is not affected by phosphorylation state of SF2/ASF. Species cross-reactivity: Human (HeLa cells), mouse and rat. Cross-reactivity expected with other species because SF2/ASF is highly conserved.
Epitope
Recognizes the N-terminal portion (aa1-97) of the SF2/ASF protein comprising the RNA-recognition motif (RRM1). Reactivity is not affected by phosphorylation state of SF2/ASF. Species cross-reactivity: Human (HeLa cells), mouse and rat. Cross-reactivity expected with other species because SF2/ASF is highly conserved.
Gene Name
SRSF1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Origin Species
Human

Immunogen

Immunogen
Recombinant SF2/ASF protein.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.09% Sodium Azide
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells. Egesipe AL, Blondel S, Cicero AL, Jaskowiak AL, Navarro C, Sandre-Giovannoli A, Levy N, Peschanski M, Nissan X. NPJ aging and mechanisms of disease. 2017 November;2:16026. PubMed: 28721276 PMC: PMC5515002

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