LSBio
IHC-plus™ GPR50 Antibody (C-Terminus)

Anti-GPR50 antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GPR50 Antibody (C-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
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$403.00each
Catalog Number: LS-A6621-50

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Overview

Description
GPR50 antibody LS-A6621 is an unconjugated rabbit polyclonal antibody to human GPR50 (C-Terminus). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IHC
Reactivity
Hu
Predicted Reactivity
Non-Human Primate
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
G protein-coupled receptor 50 | Mel1c | GPR50 | Melatonin-related receptor | MTNRL | H9
Recommended Dilution: IHC-P
3 - 28 µg/ml
UniProt Number
Q13585
NCBI GenBank
NM_004224 | NP_004215.2
SwissProt
Q13585

Target

Target
GPR50
Antigen Species
Human
Specificity
Human GPR50. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Epitope
Human GPR50. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
GPR50

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 20 amino acid peptide from C-Terminus of human GPR50. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (95%); Marmoset (90%); Gibbon (85%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization. Levoye A, Dam J, Ayoub MA, Guillaume JL, Couturier C, Delagrange P, Jockers R. The EMBO journal. 2006;25:3012-23. PubMed: 16778767 PMC: PMC1500982
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