Human Kidney: Formalin Fixed, Paraffin Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ GAPDH Antibody (clone 6C5)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Monoclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:	Rabbit
Format:	Liquid

$383.00each

Catalog Number: LS-B11003-100

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Quantity

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Overview

Description: GAPDH antibody LS-B11003 is an unconjugated mouse monoclonal antibody to rabbit GAPDH. Validated for ELISA, IF, IHC, IP and WB.
Application: ELISA, IF, IHC, IHC-F, IHC-P, IP, WB
Reactivity: Rb
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: A1 40 kd subunit | Activator 1 40 kd subunit | G3PD | GAPD | G3pdh | Rfc40 | Rf-c 40 kd subunit | GAPDH
Recommended Dilution: IHC-P: 10 µg/ml
UniProt Number: P04406
NCBI GenBank: NM_002046 | NP_002037.2
SwissProt: P04406

Target

Target: GAPDH
Antigen Species: Rabbit
Specificity: Recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin.
Epitope: Recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin.
Gene Name: GAPDH

Antibody

Host Species: Mouse
Clonality: Monoclonal
Clone: 6C5
Origin Species: Human

Immunogen

Immunogen: Rabbit muscle GAPDH

Format

Conjugate/Label: Unconjugated
Format: Liquid
Formulation: PBS, 0.09% Sodium Azide
Concentration: 1 mg/mL
Animal Free: No
Carrier-Free: Yes
Preservative: Yes
Purification Method: Protein A Affinity

Storage & Handling

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS